What Doptelet is and what it is used
What Doptelet is and what it is used
Blog Article
Doptelet contains an active substance called avatrombopag. It belongs to a group of medicines called
thrombopoietin receptor agonists.
Doptelet is used in adults with chronic liver disease to treat low platelet count (called
thrombocytopenia) before having a medical procedure where there is a risk of bleeding.
Doptelet is used to treat Avalet 20 mg (Avatrombopag) adults with low platelet counts due to primary chronic immune
thrombocytopenia (ITP) when a prior treatment for ITP (such as corticosteroids or immunoglobulins)
has not worked well enough.
Doptelet works by helping to increase the number of platelets in the blood. Platelets are blood cells
that help the blood to clot and so reduce or prevent bleeding.
2. What you need to know before you take Doptelet
Do not take Doptelet
- if you are allergic to avatrombopag or any of the other ingredients of this medicine (listed in
section 6). If you are not sure, talk to your doctor or pharmacist before taking Doptelet.
Warnings and precautions
Talk to your doctor or pharmacist before taking Doptelet if:
- you are at risk of blood clots in your veins or arteries, or members of your family have had
blood clots.
- you have another blood condition known as myelodysplastic syndrome (MDS); taking Doptelet
may worsen MDS.
You may be at higher risk of blood clots as you get older or if:
- you have had to stay in bed for a long time
- you have cancer
- you are taking the contraceptive birth control pill or hormone replacement therapy
- you have recently had surgery or been injured
- you are very overweight
- you smoke
- you have advanced chronic liver disease.
If any of the above applies to you, or you are not sure, talk to your doctor or pharmacist before taking
Doptelet.
Blood tests for platelet count
If you stop taking Doptelet, your platelet count is likely to become low as before treatment or even
lower, with a risk of bleeding. This may happen within days. The platelet count will be monitored,
and your doctor will discuss appropriate precautions with you.
Tests to check your bone marrow
In people who have problems with their bone marrow, medicines like Doptelet could make the
problems worse. Signs of bone marrow changes may show up as abnormal results in your blood tests.
Your doctor may also carry out a test to directly check your bone marrow during treatment with
Doptelet.
Children and adolescents
Do not give Doptelet to people less than 18 years old. The safety and effectiveness of this medicine in
this age group is not known.
Other medicines and Doptelet
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other
medicines.
If you are taking other medicines for ITP, you may need to take a lower dose or to stop taking them
while you are taking Doptelet.
Pregnancy and breast-feeding
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or
pharmacist for advice before taking this medicine. Doptelet is not recommended in pregnancy and in
women who are able to have children and are not using contraception.
If you are breast-feeding, ask your doctor or pharmacist for advice before taking Doptelet. This
medicine can pass into breast milk. Your doctor will help you decide whether the benefit of
breast-feeding outweighs any possible risks to your baby while you are breast-feeding.
Driving and using machines
Doptelet is not expected to affect you being able to drive, cycle or use tools or machines.
Doptelet contains lactose
Doptelet contains lactose (a type of sugar). If you have been told by your doctor that you have an
intolerance to some sugars, contact your doctor before taking this medicine.
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